What can a handful of toothpicks teach students about the science of life? Quite a bit, as AP Biology students discovered during an interactive experiment in Mrs. Ashley Morris’ class. Using toothpicks to simulate enzyme activity under normal conditions, in the presence of a competitive inhibitor, and after denaturation, students investigated how different factors affect enzyme efficiency. This hands-on approach transformed complex biological concepts into an engaging learning experience, deepening students’ understanding of the essential role enzymes play in living organisms.